A database of hormones and their receptors

Peptide Hormone

HMRbase accession number	11159
Swiss-prot Accession number	P47851 (Sequence in FASTA format)
Description	Gastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10)].
Source organism	Ovis aries (Sheep)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear
Protein Length	134 Amino acids
Molecular weight	14855
References	1 PubMed abstract 7988429
Domain Name	Bombesin
Hormone Name	Gastrin-releasing peptide
Mature Hormone Sequence	APVTAGRAGALAKMYTRGNHWAVGHLM
Position of mature hormone in Pre-Hormone protein	27 Residues from position (24-50)
Receptor	N/A
Gene ID	443332
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated