A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 11181 |
| Swiss-prot Accession number | O57312 (Sequence in FASTA format) |
| Description | Cholecystokinins precursor (CCK) [Contains: Cholecystokinin 8 (CCK8)]. |
| Source organism | Paralichthys olivaceus (Japanese flounder) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Pleuronectiformes;Pleuronectoidei; Paralichthyidae; Paralichthys. |
| Subcellular location | Secreted (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the gastrin/cholecystokinin family. |
| Tissue Specificity | N/A |
| Post translational modification | The precursor is cleaved by enzymes to produce a number of active cholecystokinins (By similarity). |
| Function | This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear |
| Protein Length | 135 Amino acids |
| Molecular weight | 14773 |
| References | 1 PubMed abstract 11042006 |
| Domain Name | Gastrin |
| Hormone Name | Cholecystokinin |
| Mature Hormone Sequence | HPISSQHLDEGQRSISTPSEALLEADTHSLGEPHLRQSRSAPQLKSLPVAEEDGDSRANLSELLARLISSRKGSVRRNSTAYSKGLSPNHRIADRDYLGWMDFGRRSAEEYEYSS |
| Position of mature hormone in Pre-Hormone protein | 115 Residues from position (21-135) |
| Receptor | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |