A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 11202 |
| Swiss-prot Accession number | P01161 (Sequence in FASTA format) |
| Description | Atrial natriuretic factor precursor (ANF) (Atrial natriuretic peptide)(ANP) (Prepronatriodilatin) [Contains: Auriculin-B; Auriculin-A;Atriopeptin-1 (Atriopeptin I); Atriopeptin-2 (Atriopeptin II);Atriopeptin-3 (Atriopeptin III)]. |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Secreted |
| Developmental Stage | N/A |
| Similarity | Belongs to the natriuretic peptide family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | A potent vasoactive substance which is thought to play a key role in cardiovascular homeostasis. Has a cGMP-stimulating activity |
| Protein Length | 152 Amino acids |
| Molecular weight | 16556 |
| References | 1 PubMed abstract 6547210 2 PubMed abstract 6328328 3 PubMed abstract 6234658 4 PubMed abstract 6239103 5 PubMed abstract 2985557 6 PubMed abstract 6238331 7 PubMed abstract 2962707 8 PubMed abstract 2951736 9 PubMed abstract 6233494 10 PubMed abstract 6419347 11 PubMed abstract 6232612 12 PubMed abstract 2966345 13 PubMed abstract 15117952 |
| Domain Name | ANP |
| Hormone Name | Auriculin-B |
| Mature Hormone Sequence | RSSCFGGRIDRIGAQSGLGCNSFRY |
| Position of mature hormone in Pre-Hormone protein | 25 Residues from position (126-150) |
| Receptor | N/A |
| Gene ID | 24602 |
| PDB ID | 1T34 |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |