A database of hormones and their receptors |
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| HMRbase accession number | 11387 |
| Swiss-prot Accession number | P07492 (Sequence in FASTA format) |
| Description | Gastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10)]. |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Secreted |
| Developmental Stage | N/A |
| Similarity | Belongs to the bombesin/neuromedin-B/ranatensin family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | GRP stimulates gastrin release as well as other gastrointestinal hormones |
| Protein Length | 148 Amino acids |
| Molecular weight | 16144 |
| References | 1 PubMed abstract 3001723 2 PubMed abstract 3211139 3 PubMed abstract 3003116 4 PubMed abstract 15489334 |
| Domain Name | Bombesin |
| Hormone Name | Gastrin-releasing peptide |
| Mature Hormone Sequence | VPLPAGGGTVLTKMYPRGNHWAVGHLM |
| Position of mature hormone in Pre-Hormone protein | 27 Residues from position (24-50) |
| Receptor | P30550
Detail in HMRbase |
| Gene ID | 2922 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |