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Peptide Hormone

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HMRbase accession number11389
Swiss-prot Accession numberP08998 (Sequence in FASTA format)
DescriptionSomatotropin precursor (Growth hormone).
Source organismGallus gallus (Chicken)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the somatotropin/prolactin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGrowth hormone plays an important role in growth control
Protein Length216 Amino acids
Molecular weight24713
References1  PubMed abstract 3174454
2   Zhvirblis G.S., Gorbulev V.G., Rubtsov P.M., Karapetyan R.V.,Zhuravlev I.V., Fisinin V.I., Skryabin K.G., Baev A.A.; "Genetic engineering of peptide hormones: I. Cloning and primarystructure of cDNA of chicken growth hormone."; Mol. Biol. (Mosk.) 21:1324-1328(1987).
3  PubMed abstract 3482121
4  PubMed abstract 1975228
5  PubMed abstract 1555772
6   Ip S.C.Y., Chan C., Leung F.C.; "Chicken growth hormone genomic sequence (Yellow Wai Chow strain)."; Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
7  PubMed abstract 12960021
8   Sun B., Nie Q., Lei M., Zhang X.; "Single nucleotide polymorphisms of chicken whole growth hormone geneand their relation to growth traits."; Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
Domain NameHormone_1  
Hormone NameSomatotropin
Mature Hormone SequenceTFPAMPLSNLFANAVLRAQHLHLLAAETYKEFERTYIPEDQRYTNKNSQAAFCYSETIPAPTGKDDAQQKSDMELLRFSLVLIQSWLTPVQYLSKVFTNNLVFGTSDRVFEKLKDLEEGIQALMRELEDRSPRGPQLLRPTYDKFDIHLRNEDALLKNYGLLSCFKKDLHKVETYLKVMKCRRFGESNCTI
Position of mature hormone in Pre-Hormone protein191 Residues from position (26-216)
ReceptorQ02092    Detail in HMRbase   
Gene ID378781      
PDB IDN/A
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