A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 11399 |
| Swiss-prot Accession number | P11384 (Sequence in FASTA format) |
| Description | Secretin precursor. |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Secreted |
| Developmental Stage | N/A |
| Similarity | Belongs to the glucagon family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Stimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich bile and inhibits HCl production by the stomach |
| Protein Length | 134 Amino acids |
| Molecular weight | 15072 |
| References | 1 PubMed abstract 2315322 2 PubMed abstract 1711228 3 PubMed abstract 2061329 4 PubMed abstract 2719704 |
| Domain Name | Hormone_2 |
| Hormone Name | Secretin |
| Mature Hormone Sequence | HSDGTFTSELSRLQDSARLQRLLQGLV |
| Position of mature hormone in Pre-Hormone protein | 27 Residues from position (33-59) |
| Receptor | P23811
Detail in HMRbase |
| Gene ID | 24769 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |