A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 20018 |
| Swiss-prot Accession number | Q05192 (Sequence in FASTA format) |
| Description | Nuclear hormone receptor FTZ-F1 beta (dHR39). |
| Source organism | Drosophila melanogaster (Fruit fly) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
| Subcellular location | Nucleus |
| Developmental Stage | Expressed at all stages. |
| Similarity | Belongs to the nuclear hormone receptor family. NR5 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Expressed throughout the blastodermal layer in early embryos. At later stages, strong expression is observed in the brain, ventral cord and hindgut. |
| Post translational modification | N/A |
| Function | Acts as a cofactor to fushi tarazu (ftz). Facilitates the binding of ftz to DNA. Binds the sequence element 5'- YCYYGGYCR-3' in the zebra element of ftz. Probably also functions as a receptor for a yet unknown ligand. |
| Protein Length | 808 Amino acids |
| Molecular weight | 87314 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 8382937 2 PubMed abstract 8479913 3 PubMed abstract 10731132 4 PubMed abstract 12537572 5 PubMed abstract 12537569 6 PubMed abstract 8164672 |
| Hormone | N/A |
| Gene ID | 35398 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |