A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 20035 |
| Swiss-prot Accession number | Q2Q421 (Sequence in FASTA format) |
| Description | EGF-like module-containing mucin-like hormone receptor-like 2precursor (EGF-like module EMR2) (CD312 antigen). |
| Source organism | Canis familiaris (Dog) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 5 EGF-like domains. Contains 1 GPS domain. |
| Tissue Specificity | N/A |
| Post translational modification | Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit (By similarity). |
| Function | Receptor probably involved in cell attachment (By similarity). |
| Protein Length | 830 Amino acids |
| Molecular weight | 91452 |
| Domain Name | 7tm_2 EGF_CA GPS EGF |
| References | 1 Kwakkenbos M.J., Matmati M., Pouwels W., Wang Y., Bontrop R.E.,Heidt P.J., Hoek R.M., Hamann J.; "A unique mode of concerted evolution of the EGF-TM7 receptor chimeraEMR2."; Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
|
| Hormone | N/A |
| Gene ID | 610750 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |