A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20057 |
| Swiss-prot Accession number | P49869 (Sequence in FASTA format) |
| Description | Probable nuclear hormone receptor HR38 (dHR38). |
| Source organism | Drosophila melanogaster (Fruit fly) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
| Subcellular location | Nucleus |
| Developmental Stage | Low levels in 0-8 hours embryos and adults. Higher in late embryogenesis and during larval and pupal stages. Short isoform is enriched in pupae and adults, long isoform in larvae. |
| Similarity | Belongs to the nuclear hormone receptor family. NR4 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Ubiquitously expressed in preblastoderm embryos, specifically in central nervous system and intestinal tract. Highly expressed in third instar larval imaginal disks and brain complexes, but not in ovaries. |
| Post translational modification | N/A |
| Function | Binds to NGFI-B response elements. Plays an important role in late stages of epidermal metamorphosis. |
| Protein Length | 1073 Amino acids |
| Molecular weight | 116992 |
| Domain Name | zf-C4 Hormone_recep |
| References | 1 PubMed abstract 7644522 2 PubMed abstract 9704500 3 PubMed abstract 9649534 4 PubMed abstract 10731132 5 PubMed abstract 12537572 6 PubMed abstract 7479849 |
| Hormone | N/A |
| Gene ID | 35332 |
| PDB ID | 1PDU |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |