A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20062 |
| Swiss-prot Accession number | Q24142 (Sequence in FASTA format) |
| Description | Nuclear hormone receptor HR78 (dHR78) (Nuclear receptor XR78E/F). |
| Source organism | Drosophila melanogaster (Fruit fly) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
| Subcellular location | Nucleus |
| Developmental Stage | Highest expression in third instar larvae and prepupae. |
| Similarity | Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Binds to direct repeats of the sequence 5'-AGGTCA-3'. Inhibits the ecdysone response. Plays an essential role in regulating molting of the tracheal cuticle during larval development. |
| Protein Length | 601 Amino acids |
| Molecular weight | 65393 |
| Domain Name | zf-C4 Hormone_recep |
| References | 1 PubMed abstract 7479849 2 PubMed abstract 7479823 3 PubMed abstract 10731132 4 PubMed abstract 12537572 5 PubMed abstract 12537569 6 PubMed abstract 14599492 |
| Hormone | N/A |
| Gene ID | 40378 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |