A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 20065 |
| Swiss-prot Accession number | P16235 (Sequence in FASTA format) |
| Description | Lutropin-choriogonadotropic hormone receptor precursor (LH/CG-R) (LSH-R) (Luteinizing hormone receptor). |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Cell membrane; multi-pass membrane protein. Secreted protein. Note=Some isoforms may be secreted |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 7 LRR (leucine-rich) repeats. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
| Protein Length | 700 Amino acids |
| Molecular weight | 78036 |
| Domain Name | 7tm_1 LRR_1 |
| References | 1 PubMed abstract 2502842 2 PubMed abstract 1353463 3 PubMed abstract 2019252 4 PubMed abstract 1976554 5 PubMed abstract 2281186 6 PubMed abstract 2040640 7 PubMed abstract 2174034 8 PubMed abstract 2601325 9 PubMed abstract 2925659 10 PubMed abstract 1714448 11 PubMed abstract 7776964 |
| Hormone | N/A |
| Gene ID | 25477 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |