A database of hormones and their receptors |
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| HMRbase accession number | 20157 |
| Swiss-prot Accession number | P12813 (Sequence in FASTA format) |
| Description | Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclearhormone receptor NUR/77) (N10 nuclear protein). |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Nucleus |
| Developmental Stage | Highest levels are found in the adult with barely detectable levels in pre- and early postnatal tissue. |
| Similarity | Belongs to the nuclear hormone receptor family. NR4 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Highest levels occur in the testis followed by brain and muscle tissue. |
| Post translational modification | N/A |
| Function | Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. |
| Protein Length | 601 Amino acids |
| Molecular weight | 64738 |
| Domain Name | zf-C4 Hormone_recep |
| References | 1 PubMed abstract 3186734 2 PubMed abstract 2555161 3 PubMed abstract 15489334 |
| Hormone | N/A |
| Gene ID | 15370 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |