A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 20168 |
| Swiss-prot Accession number | Q91V95 (Sequence in FASTA format) |
| Description | Parathyroid hormone receptor precursor (PTH2 receptor). |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 2 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTHR2 may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTHR2 presence in neurons indicates that it may function as a neurotransmitter receptor (By similarity). |
| Protein Length | 546 Amino acids |
| Molecular weight | 61908 |
| Domain Name | 7tm_2 HRM |
| References | 1 PubMed abstract 11471062 2 PubMed abstract 16141072 3 PubMed abstract 11861531 |
| Hormone | N/A |
| Gene ID | 213527 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |