| HMRbase accession number | 20172 |
| Swiss-prot Accession number | A0EQL2 (Sequence in FASTA format) |
| Description | Sex hormone-binding globulin precursor (SHBG). |
| Source organism | Crocuta crocuta (Spotted hyena) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Hyaenidae;Crocuta. |
| Subcellular location | Secreted protein (By similarity). Note=In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis (By similarity) |
| Developmental Stage | N/A |
| Similarity | Contains 2 laminin G-like domains. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration (By similarity). |
| Protein Length | 393 Amino acids |
| Molecular weight | 42443 |
| Domain Name | Laminin_G_1 Laminin_G_2 |
| References | 1 Miguel-Queralt S., Yalcinkaya T.M., Avvakumov G.V., Place N.,Siiteri P.K., Glickman S.E., Hammond G.L.; "Unusual steroid-binding properties of hyena sex hormone-bindingglobulin."; Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
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| Hormone | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
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