A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20175 |
| Swiss-prot Accession number | Q62588 (Sequence in FASTA format) |
| Description | Sex hormone-binding globulin precursor (SHBG) (Sex steroid-bindingprotein) (SBP) (Testis-specific androgen-binding protein) (ABP). |
| Source organism | Phodopus sungorus (Striped hairy-footed hamster) (Djungarian hamster) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Phodopus. |
| Subcellular location | Secreted protein (By similarity). Note=In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis (By similarity) |
| Developmental Stage | N/A |
| Similarity | Contains 2 laminin G-like domains. |
| Tissue Specificity | N/A |
| Post translational modification | Differentially glycosylated in liver (SHBG) and testis (ABP). |
| Function | Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration (By similarity). |
| Protein Length | 399 Amino acids |
| Molecular weight | 43842 |
| Domain Name | Laminin_G_1 Laminin_G_2 |
| References | 1 PubMed abstract 7495693 2 PubMed abstract 9462298 |
| Hormone | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |