A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20195 |
| Swiss-prot Accession number | P10827 (Sequence in FASTA format) |
| Description | Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7)(EAR7). |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Nuclear hormone receptor. High affinity receptor for triiodothyronine. |
| Protein Length | 490 Amino acids |
| Molecular weight | 54816 |
| Domain Name | zf-C4 Hormone_recep |
| References | 1 PubMed abstract 1850510 2 PubMed abstract 2539258 3 PubMed abstract 3357890 4 PubMed abstract 3684612 5 PubMed abstract 2464749 6 PubMed abstract 15489334 7 PubMed abstract 3672126 8 Liu C., Li L., Liu B., Zang X.; Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases. 9 PubMed abstract 9267036 10 PubMed abstract 9627117 11 PubMed abstract 10567404 |
| Hormone | Detail in HMRbase Detail in HMRbase |
| Gene ID | 7067 |
| PDB ID | 1NAV 2H79 |
| Drugpedia | wiki |
| Comments |