| HMRbase accession number | 20197 |
| Swiss-prot Accession number | O57606 (Sequence in FASTA format) |
| Description | Thyroid hormone receptor alpha. |
| Source organism | Necturus maculosus (Mudpuppy) (Waterdog) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Caudata; Salamandroidea; Proteidae; Necturus. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | A high level expression seen in the gills, intestine and muscles. |
| Post translational modification | N/A |
| Function | High affinity receptor for triiodothyronine. |
| Protein Length | 408 Amino acids |
| Molecular weight | 46922 |
| Domain Name | zf-C4 Hormone_recep |
| References | 1 Safi R., Vlaeminck V., Duffraisse M., Plateroti M., Carreghi A.,De Luze A., Duterque-Coquillaud M., Demeneix B., Laudet V.; "Neoteny revisited: thyroid hormone receptors are functional in themudpuppy (Necturus maculosus), an obligatory neotene."; Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 9169551
|
| Hormone | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
A database of hormones and their receptors