A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20201 |
| Swiss-prot Accession number | Q02777 (Sequence in FASTA format) |
| Description | Thyroid hormone receptor alpha. |
| Source organism | Rana catesbeiana (Bull frog) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana. |
| Subcellular location | Nucleus |
| Developmental Stage | Expression is low at stage XII of tadpole development, greatly increases by stage XIX, decreases thereafter and is relatively low by stage XXIV, when metamorphosis is almost complete. |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Highest level of expression in erythrocytes. Also expressed in liver, tail, eye, muscle and skin. |
| Post translational modification | N/A |
| Function | High affinity receptor for triiodothyronine. |
| Protein Length | 418 Amino acids |
| Molecular weight | 47748 |
| Domain Name | zf-C4 Hormone_recep |
| References | 1 PubMed abstract 8243269 2 PubMed abstract 1645454 |
| Hormone | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |