A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20413 |
| Swiss-prot Accession number | Q8IXH9 (Sequence in FASTA format) |
| Description | 5-hydroxytryptamine 4 receptor subunit b. |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Membrane (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
| Protein Length | 388 Amino acids |
| Molecular weight | 43789 |
| Domain Name | 7tm_1 |
| References | 1 Bruss M., Bonisch H.; "Molecular cloning and pharmacological characterization of human 5-HT4-like receptors."; Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases.
2 Bruess M.; Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases. |
| Hormone | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |