A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20432 |
| Swiss-prot Accession number | P56450 (Sequence in FASTA format) |
| Description | Melanocortin receptor 4 (MC4-R). |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase. |
| Protein Length | 332 Amino acids |
| Molecular weight | 36989 |
| Domain Name | 7tm_1 |
| References | 1 Dumont L.M., Wu C.S., Mountjoy K.G.; "Characterization of the melanocortin-4 receptor gene."; Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases.
2 Morooka Y., Oomizu S., Takeuchi S., Takahashi S.; Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases. |
| Hormone | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |