A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 20433 |
| Swiss-prot Accession number | O97504 (Sequence in FASTA format) |
| Description | Melanocortin receptor 4 (MC4-R). |
| Source organism | Sus scrofa (Pig) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
| Protein Length | 332 Amino acids |
| Molecular weight | 36947 |
| Domain Name | 7tm_1 |
| References | 1 Ito Y., Minezawa M.; Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 10656927 3 Matteri R.L., Dyer C.J.; Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases. |
| Hormone | N/A |
| Gene ID | 397359 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |