A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20657 |
| Swiss-prot Accession number | P49285 (Sequence in FASTA format) |
| Description | Melatonin receptor type 1A (MEL-1A-R) (CKA). |
| Source organism | Gallus gallus (Chicken) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Expressed in optic tectum and retina, less in neostriatum, hypothalamus and thalamus. |
| Post translational modification | N/A |
| Function | High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity (By similarity). |
| Protein Length | 353 Amino acids |
| Molecular weight | 39896 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 7576645 |
| Hormone | N/A |
| Gene ID | 396319 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |