A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20663 |
| Swiss-prot Accession number | Q8CIQ6 (Sequence in FASTA format) |
| Description | Melatonin receptor type 1B (Mel-1B-R) (Mel1b melatonin receptor). |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity (By similarity). |
| Protein Length | 364 Amino acids |
| Molecular weight | 40261 |
| Domain Name | 7tm_1 |
| References | 1 Jin X., von Gall C., Pieschl R.L., Gribkoff V.K., Stehle J.H.,Reppert S.M., Weaver D.R.; "Targeted disruption of the mouse Mel1b melatonin receptor."; Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
2 Resuehr D., Olcese J.; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 12679517 |
| Hormone | N/A |
| Gene ID | 244701 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |