A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20665 |
| Swiss-prot Accession number | P49219 (Sequence in FASTA format) |
| Description | Melatonin receptor type 1C (MEL-1C-R). |
| Source organism | Xenopus laevis (African clawed frog) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | High affinity receptor for melatonin. Likely to mediate the potent effects of melatonin on pigment aggregation in melanophores. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. |
| Protein Length | 420 Amino acids |
| Molecular weight | 47425 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 7517042 |
| Hormone | N/A |
| Gene ID | 397808 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |