A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 20715 |
| Swiss-prot Accession number | P32301 (Sequence in FASTA format) |
| Description | Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R)(GLP-1R). |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 2 family. |
| Tissue Specificity | Pancreatic islets, stomach, lung, rat insulinoma cell line. |
| Post translational modification | N/A |
| Function | This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
| Protein Length | 463 Amino acids |
| Molecular weight | 52877 |
| Domain Name | 7tm_2 HRM |
| References | 1 PubMed abstract 1326760 2 PubMed abstract 7813606 3 PubMed abstract 1326760 4 PubMed abstract 7813606 |
| Hormone | N/A |
| Gene ID | 25051 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |