A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20773 |
| Swiss-prot Accession number | P22086 (Sequence in FASTA format) |
| Description | Alpha-2C adrenergic receptor (Alpha-2C adrenoceptor) (Alpha-2Cadrenoreceptor) (Alpha-2 adrenergic receptor subtype C4). |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
| Protein Length | 458 Amino acids |
| Molecular weight | 49864 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 1704126 2 PubMed abstract 1704314 3 PubMed abstract 1645350 4 Saitoh M., Imai A., Shimomura H.; "Cloning of rat alpha-2-B-adrenergic receptor gene and expression inrat submandibular gland."; Shigaku 80:317-326(1992). |
| Hormone | N/A |
| Gene ID | 24175 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |