A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20847 |
| Swiss-prot Accession number | O42385 (Sequence in FASTA format) |
| Description | 5-hydroxytryptamine 1A-alpha receptor (5-HT-1A-alpha) (Serotoninreceptor 1A-alpha) (5-HT1A-alpha) (F1A). |
| Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
| Protein Length | 423 Amino acids |
| Molecular weight | 47001 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 9218723 |
| Hormone | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |