A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20850 |
| Swiss-prot Accession number | Q8JG69 (Sequence in FASTA format) |
| Description | Alpha-2Db adrenergic receptor (Alpha-2Db adrenoceptor) (Alpha-2Dbadrenoreceptor) (Alpha(2Db)AR). |
| Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is dexmedetomidine > norepinephrine = epinephrine > oxymetazoline. |
| Protein Length | 415 Amino acids |
| Molecular weight | 46863 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 12949138 2 PubMed abstract 15655522 |
| Hormone | N/A |
| Gene ID | 266755 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |