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Search Result - 1

HMRbase accession number20856
Swiss-prot Accession numberP37288 (Sequence in FASTA format)
DescriptionVasopressin V1a receptor (V1aR) (Vascular/hepatic-type argininevasopressin receptor) (Antidiuretic hormone receptor 1a) (AVPR V1a).
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationMembrane; multi-pass membrane protein
Developmental StageN/A
Similarity Belongs to the G-protein coupled receptor 1 family.
Tissue SpecificityN/A
Post translational modification N/A
Function Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.
Protein Length418 Amino acids
Molecular weight46800
Domain Name7tm_1  DUF1856  
References1  PubMed abstract 8106369
2  PubMed abstract 8074728
3  PubMed abstract 9357056
4  PubMed abstract 9581826
5   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
6  PubMed abstract 15489334
7  PubMed abstract 12082568
8  PubMed abstract 16511036
9  PubMed abstract 8106369
10  PubMed abstract 8074728
11  PubMed abstract 9357056
12  PubMed abstract 9581826
13   Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
14  PubMed abstract 15489334
15  PubMed abstract 12082568
16  PubMed abstract 16511036
HormoneN/A
Gene ID552      
PDB ID1YTV      
Drugpediawiki
Comments!Hormone for this Receptor are either unknown or have not yet been curated