A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 20914 |
| Swiss-prot Accession number | Q864K8 (Sequence in FASTA format) |
| Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
| Source organism | Hylobates lar (Common gibbon) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hylobatidae; Hylobates. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
| Protein Length | 317 Amino acids |
| Molecular weight | 34824 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 12687585 2 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 12687585 4 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. |
| Hormone | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |