A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21007 |
| Swiss-prot Accession number | P30559 (Sequence in FASTA format) |
| Description | Oxytocin receptor (OT-R). |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. |
| Protein Length | 389 Amino acids |
| Molecular weight | 42772 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 1313946 2 Kimura T., Tanizawa O., Mori K., Brownstein M.J., Okayama H.; Nature 357:176-176(1992). 3 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 7798245 5 PubMed abstract 1313946 6 Kimura T., Tanizawa O., Mori K., Brownstein M.J., Okayama H.; Nature 357:176-176(1992). 7 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases. 8 PubMed abstract 7798245 |
| Hormone | P01178 Detail in HMRbase |
| Gene ID | 5021 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |