A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21052 |
| Swiss-prot Accession number | P49683 (Sequence in FASTA format) |
| Description | Prolactin-releasing peptide receptor (PrRP receptor) (PrRPR) (G-protein coupled receptor 10) (hGR3). |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Only detected in the pituitary gland and in all cell types of pituitary adenomas. |
| Post translational modification | N/A |
| Function | Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing. |
| Protein Length | 370 Amino acids |
| Molecular weight | 41107 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 8666380 2 PubMed abstract 9607765 3 PubMed abstract 11923475 4 PubMed abstract 15164054 5 PubMed abstract 15489334 6 PubMed abstract 10498338 7 PubMed abstract 11641419 8 PubMed abstract 8666380 9 PubMed abstract 9607765 10 PubMed abstract 11923475 11 PubMed abstract 15164054 12 PubMed abstract 15489334 13 PubMed abstract 10498338 14 PubMed abstract 11641419 |
| Hormone | P81277 Detail in HMRbase |
| Gene ID | 2834 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |