A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21058 |
| Swiss-prot Accession number | P70031 (Sequence in FASTA format) |
| Description | Cholecystokinin receptor (CCK-XLR). |
| Source organism | Xenopus laevis (African clawed frog) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Brain and stomach. |
| Post translational modification | N/A |
| Function | Receptor for cholecystokinin. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Has high affinity for CCK-8 and low affinities for gastrin-17-I, CCK-4, and unsulfated CCK-8. |
| Protein Length | 453 Amino acids |
| Molecular weight | 51157 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 8700154 2 PubMed abstract 8700154 |
| Hormone | P50144 Detail in HMRbase P50145 Detail in HMRbase |
| Gene ID | 378563 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |