A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21063 |
| Swiss-prot Accession number | Q01717 (Sequence in FASTA format) |
| Description | Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberinreceptor). |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. |
| Protein Length | 412 Amino acids |
| Molecular weight | 46609 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 1317787 2 PubMed abstract 1377915 3 PubMed abstract 8387312 4 PubMed abstract 1338727 5 PubMed abstract 8275956 6 PubMed abstract 7509436 7 PubMed abstract 1373613 8 PubMed abstract 1334485 |
| Hormone | P01150 Detail in HMRbase |
| Gene ID | 25570 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |