A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21079 |
| Swiss-prot Accession number | Q28172 (Sequence in FASTA format) |
| Description | Prolactin receptor precursor (PRL-R). |
| Source organism | Bos taurus (Bovine) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
| Subcellular location | Membrane; Single-pass type I membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 2 fibronectin type-III domains. |
| Tissue Specificity | Expressed in all tissues examined; liver, peripheral blood lymphocytes, endometrium, corpus luteum, intestine, fetal thymus, fetal spleen, fetal liver and fetal brain. |
| Post translational modification | N/A |
| Function | This is a receptor for the anterior pituitary hormone prolactin. |
| Protein Length | 581 Amino acids |
| Molecular weight | 65153 |
| Domain Name | fn3 |
| References | 1 PubMed abstract 1338725 2 PubMed abstract 9231767 3 PubMed abstract 7738463 4 PubMed abstract 9343303 |
| Hormone | P01239 Detail in HMRbase |
| Gene ID | 281422 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |