A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21221 |
| Swiss-prot Accession number | P10589 (Sequence in FASTA format) |
| Description | RecName: COUP transcription factor 1;Alternative Name: COUP-TF I;Alternative Name: COUP-TF1;Alternative Name: Nuclear receptor subfamily 2 group F member 1;Alternative Name: V-ERBA-related protein EAR-3; |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Nucleus (Potential) |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif. |
| Protein Length | 423 Amino acids |
| Molecular weight | 46156 |
| Domain Name | Hormone_recep zf-C4 zf-C4_C |
| References | 1 PubMed abstract 2739739 2 PubMed abstract 2905047 3 PubMed abstract 15489334 4 PubMed abstract 10207062 |
| Hormone | N/A |
| Gene ID | 7025 |
| PDB ID | 2EBL |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |