A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21234 |
| Swiss-prot Accession number | P45447 (Sequence in FASTA format) |
| Description | RecName: Ecdysone-induced protein 78C;DR-78;Alternative Name: Nuclear receptor subfamily 1 group E member 1; |
| Source organism | Drosophila melanogaster (Fruit fly) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora. |
| Subcellular location | Nucleus (Probable) |
| Developmental Stage | Isoform A is expressed only in mid-pupal stages, while isoform B is maximally expressed in newly formed prepupae and immediately following isoform A in mid-pupae. |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Induces the early late puff 78C which triggers puparium formation and development. |
| Protein Length | 866 Amino acids |
| Molecular weight | 95250 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 8402914 2 PubMed abstract 8878682 3 PubMed abstract 10731132 4 PubMed abstract 12537572 5 PubMed abstract 8241283 |
| Hormone | Detail in HMRbase |
| Gene ID | 40345 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |