A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21242 |
| Swiss-prot Accession number | P15370 (Sequence in FASTA format) |
| Description | RecName: Protein embryonic gonad;Alternative Name: Protein eagle;Alternative Name: Protein spready;Alternative Name: Nuclear receptor subfamily 0 group A member 3; |
| Source organism | Drosophila melanogaster (Fruit fly) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora. |
| Subcellular location | Nucleus (Potential) |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR0 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | During embryonic stages 10 and 11, expression was observed in four neuroblasts, NB2-4, NB3-3, NB6-4 and NB7-3. Except for NB6-4, expression reaches a maximum at the very beginning of expression or in the period of neuroblast delamination. Weak expression is also observed in a few putative progeny of NB7-3 during late embryonic stage 11 and 12. All eagle expression in abdominal segments disappears by stage 13. |
| Post translational modification | N/A |
| Function | May play a critical role in development of the progeny of eagle-positive neuroblasts. |
| Protein Length | 373 Amino acids |
| Molecular weight | 39561 |
| Domain Name | zf-C4 |
| References | 1 PubMed abstract 2555153 2 PubMed abstract 8625804 3 PubMed abstract 10731132 4 PubMed abstract 12537572 |
| Hormone | N/A |
| Gene ID | 40428 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |