A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 21246 |
| Swiss-prot Accession number | P62509 (Sequence in FASTA format) |
| Description | RecName: Estrogen-related receptor gamma;Alternative Name: Estrogen receptor-related protein 3;Alternative Name: Nuclear receptor subfamily 3 group B member 3; |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Nucleus (Probable) |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Highly expressed in the heart, brain and kidney and low expression in the liver. |
| Post translational modification | N/A |
| Function | Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. |
| Protein Length | 458 Amino acids |
| Molecular weight | 51306 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 10428842 2 PubMed abstract 12465718 3 PubMed abstract 16141072 4 PubMed abstract 15489334 |
| Hormone | N/A |
| Gene ID | 26381 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |