A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21317 |
| Swiss-prot Accession number | P79926 (Sequence in FASTA format) |
| Description | RecName: Hepatocyte nuclear factor 4-beta;HNF-4-beta;Alternative Name: Nuclear receptor subfamily 2 group A member 3; |
| Source organism | Xenopus laevis (African clawed frog) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
| Subcellular location | Nucleus (By similarity) |
| Developmental Stage | Maternal protein which is distributed within an animal-to-vegetal gradient in the embryo. Present from the egg stage onward and throughout the entire development. |
| Similarity | Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Expressed in liver, kidney, stomach, intestine, lung, ovary, and testis. Not expressed in fat, muscle and brain. |
| Post translational modification | N/A |
| Function | Transcription factor; binds and activates the promoter for the HNF1-alpha gene. Seems to have a lower DNA binding activity than HNF4-alpha and is a weaker transactivator than the alpha isoform. |
| Protein Length | 446 Amino acids |
| Molecular weight | 50257 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 9001222 |
| Hormone | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |