A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21320 |
| Swiss-prot Accession number | P49866 (Sequence in FASTA format) |
| Description | RecName: Transcription factor HNF-4 homolog;Alternative Name: dHNF4;Alternative Name: Nuclear receptor subfamily 2 group A member 4; |
| Source organism | Drosophila melanogaster (Fruit fly) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | In developing embryos it is expressed in mid- gut, fat bodies and the distal region of Malpighian tubules. |
| Post translational modification | N/A |
| Function | Transcriptionally controlled transcription factor. Important for the differentiation of various specialized cell types that arise from both endoderm and mesoderm. May have a role in early gut formation. |
| Protein Length | 666 Amino acids |
| Molecular weight | 71900 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 8440243 2 PubMed abstract 10731132 3 PubMed abstract 12537572 |
| Hormone | N/A |
| Gene ID | 44544 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |