A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21321 |
| Swiss-prot Accession number | P10734 (Sequence in FASTA format) |
| Description | RecName: Zygotic gap protein knirps;Alternative Name: Nuclear receptor subfamily 0 group A member 1; |
| Source organism | Drosophila melanogaster (Fruit fly) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR0 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Transcriptional repressor. Binds to multiple sites in the eve stripe 3 enhancer element. Plays an essential role in the segmentation process both by refining the expression patterns of gap genes and by establishing pair-rules stripes of gene expression. |
| Protein Length | 429 Amino acids |
| Molecular weight | 45611 |
| Domain Name | zf-C4 |
| References | 1 PubMed abstract 2904128 2 PubMed abstract 10731132 3 PubMed abstract 12537572 4 PubMed abstract 12537569 5 PubMed abstract 8670869 |
| Hormone | N/A |
| Gene ID | 40287 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |