A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21346 |
| Swiss-prot Accession number | Q15466 (Sequence in FASTA format) |
| Description | RecName: Nuclear receptor subfamily 0 group B member 2;Alternative Name: Orphan nuclear receptor SHP;Alternative Name: Small heterodimer partner; |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR0 subfamily. |
| Tissue Specificity | Liver. Low levels of expression were detected in heart and pancreas. |
| Post translational modification | N/A |
| Function | Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts. |
| Protein Length | 257 Amino acids |
| Molecular weight | 28058 |
| Domain Name | Hormone_recep |
| References | 1 PubMed abstract 8650544 2 PubMed abstract 9603951 3 PubMed abstract 11136233 4 PubMed abstract 16710414 5 PubMed abstract 15489334 6 PubMed abstract 15723037 |
| Hormone | N/A |
| Gene ID | 8431 |
| PDB ID | 1YUC 2Z4J |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |