A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21349 |
| Swiss-prot Accession number | P20393 (Sequence in FASTA format) |
| Description | RecName: Nuclear receptor subfamily 1 group D member 1;Alternative Name: V-erbA-related protein EAR-1;Alternative Name: Rev-erbA-alpha; |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Nucleus (Potential) |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Expressed in all tissues and cell lines examined. Expressed at high levels in some squamous carcinoma cell lines. |
| Post translational modification | N/A |
| Function | Functions as a constitutive transcriptional repressor. Possible receptor for triiodothyronine. |
| Protein Length | 614 Amino acids |
| Molecular weight | 66805 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 2539258 2 PubMed abstract 1971514 3 PubMed abstract 15489334 4 PubMed abstract 1850510 5 PubMed abstract 15302935 6 PubMed abstract 9660968 |
| Hormone | N/A |
| Gene ID | 9572 |
| PDB ID | 1A6Y 1EF6 1GA5 1HLZ |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |