A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 21377 |
| Swiss-prot Accession number | P13056 (Sequence in FASTA format) |
| Description | RecName: Nuclear receptor subfamily 2 group C member 1;Alternative Name: Orphan nuclear receptor TR2;Alternative Name: Testicular receptor 2 |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Nucleus (Potential) |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Orphan nuclear receptor. Represses transcription and binds DNA as a homodimer. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism (By similarity). |
| Protein Length | 483 Amino acids |
| Molecular weight | 53042 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 3421977 2 PubMed abstract 18669648 |
| Hormone | N/A |
| Gene ID | 7181 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |