A database of hormones and their receptors |
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| HMRbase accession number | 21388 |
| Swiss-prot Accession number | Q9Y5X4 (Sequence in FASTA format) |
| Description | Photoreceptor-specific nuclear receptor;Alternative Name: Retina-specific nuclear receptor;Alternative Name: Nuclear receptor subfamily 2 group E member 3 |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Eye specific; found solely in the outer nuclear layer of the adult neurosensory retina, where the nuclei of cone and rod photoreceptors reside. |
| Post translational modification | N/A |
| Function | Transcription factor that may have a role in the regulation of signaling pathways intrinsic to the photoreceptor cell function. |
| Protein Length | 410 Amino acids |
| Molecular weight | 44692 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 10220376 2 PubMed abstract 10611353 3 PubMed abstract 17081983 4 PubMed abstract 11071390 5 PubMed abstract 10655056 6 PubMed abstract 12963616 7 PubMed abstract 15459973 8 PubMed abstract 17564971 |
| Hormone | N/A |
| Gene ID | 10002 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |