A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21404 |
| Swiss-prot Accession number | Q07917 (Sequence in FASTA format) |
| Description | Nuclear receptor subfamily 4 group A member 2;Alternative Name: Orphan nuclear receptor NURR1;Alternative Name: NUR-related factor 1;Alternative Name: Regenerating liver nuclear receptor 1;RNR-1;Alternative Name: SL-322;Alternative Name: Nuclear orphan receptor HZF-3 |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR4 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Not expressed in quiescent liver but is rapidly induced following partial hepatectomy and is specific to hepatic growth as it is not induced in other mitogen-treated cells. Expressed at very low levels in the lung, spleen and stomach and at high levels in the brain. |
| Post translational modification | N/A |
| Function | Probable nuclear receptor. May confer liver-specific regulation of delayed-early genes induced later in the G1 phase of regeneration along with HMR. |
| Protein Length | 598 Amino acids |
| Molecular weight | 66622 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 7914660 2 PubMed abstract 8473329 3 PubMed abstract 9221923 |
| Hormone | N/A |
| Gene ID | 54278 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |