A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21412 |
| Swiss-prot Accession number | Q64249 (Sequence in FASTA format) |
| Description | Nuclear receptor subfamily 6 group A member 1;Alternative Name: Germ cell nuclear factor;GCNF;mGCNF;Alternative Name: Retinoid receptor-related testis-specific receptor;RTR |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Nucleus (Probable) |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR6 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Expressed in the germ cells of both the adult testis and ovary, being most abundant in spermatids. |
| Post translational modification | N/A |
| Function | Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis. |
| Protein Length | 495 Amino acids |
| Molecular weight | 55976 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 7854358 2 PubMed abstract 7835709 3 PubMed abstract 11178239 4 PubMed abstract 12606326 5 PubMed abstract 7760852 6 PubMed abstract 9025060 7 PubMed abstract 12080054 |
| Hormone | N/A |
| Gene ID | 14536 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |