A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21455 |
| Swiss-prot Accession number | P10826 (Sequence in FASTA format) |
| Description | Retinoic acid receptor beta;RAR-beta;Alternative Name: Nuclear receptor subfamily 1 group B member 2;Alternative Name: RAR-epsilon;Alternative Name: HBV-activated protein |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Isoform Beta-1: Nucleus. Isoform Beta-2: Nucleus. Isoform Beta-4: Cytoplasm |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | This is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression. |
| Protein Length | 455 Amino acids |
| Molecular weight | 50489 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 2836738 2 PubMed abstract 2825037 3 PubMed abstract 10411930 4 PubMed abstract 15489334 5 PubMed abstract 1663808 6 PubMed abstract 8275470 7 PubMed abstract 3014347 8 PubMed abstract 2170809 9 PubMed abstract 2833708 10 PubMed abstract 1321662 11 PubMed abstract 8383553 12 PubMed abstract 16959974 |
| Hormone | N/A |
| Gene ID | 5915 |
| PDB ID | 1HRA 1XAP |
| Drugpedia | wiki |
| Comments | !Hormone for this Receptor are either unknown or have not yet been curated |