A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21641 |
| Swiss-prot Accession number | Q13258 (Sequence in FASTA format) |
| Description | Prostaglandin D2 receptor;Alternative Name: Prostanoid DP receptor;Alternative Name: PGD receptor |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Cell membrane; Multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Expressed in retina and small intestine. |
| Post translational modification | N/A |
| Function | Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate. |
| Protein Length | 359 Amino acids |
| Molecular weight | 40271 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 7642548 2 PubMed abstract 15489334 3 PubMed abstract 15496624 |
| Hormone | Detail in HMRbase |
| Gene ID | 5729 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |